Clinical Documentation in Clinical Trial

A clinical trial is a clinical research which involvesinspection long after the actual study is completed.
controlled test of the new drugs or 'new invasiveThe documentation in clinical trials also has some
medical device' on human beings and is conducteddirectly related function as based on it the future
under the regulatory acts of the FDA before it isplanning, tracking and execution is done in the
made available for general public use or generalresearch-oriented work. The process of
clinical use. These clinical trials are mainlydocumentation related to the clinical trial involves
conducted to allow safety of the data to becertain rules and regulations set by the regulatory
collected for health related studies involvingbody of the country -for e.g. which in the case of
therapy protocols or related to the introduction ofUS is the FDA. The quality of data produced and
new drugs in the medical market of a particularkept in the clinical documentation should meet the
country only after a certain regulatory body hasstandards. There are certain rules to follow in
approved of it. The clinical documentation comesstoring and maintaining the data as well. There are
in very handy in these cases as it helps to keepother regulatory body as well who decides on the
in-detailed record of each happening. The clinicaltypes of documentation for each case.
trials can cover a wide range of subjects and canIn case of the clinical trial, some of the important
vary in size to one centre in a country to manydocuments are the case record forms, informed
centres in multiple countries.consent forms, protocol, investigators brochure
Since the clinical trials are research-based work,and the patient information sheet- all of which
clinical documentation plays an important role in itfollow very stringent rules ad principle that are to
and forms an integral part of the clinical research.be followed. Some of the rules for clinical
The proper documentation helps to keep properdocumentation are as follows:
track of what is happening and is important from- Labelling of all the documents along with the
the pre-clinical studies and updates documentationsdate, which should be clearly visible.
are of utmost importance in the total process of- The documents are to be arranged so that
clinical trial. The clinical documentation is needs tothey are fully reconstructable even after the
capture and attest the data collected and thestudy is completed.
authenticity of the data and its use in the clinical- All the documentations should follow the
trial. The documentation is generally preservedguidelines provided by the regulatory authorities
and helps in future reference and may help instrictly and there should be no discrepancies.